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CJC-1295

Also known as DAC:GRF and Modified GRF 1-29.

One small human study, published in 2006. No long-term human safety trial has been published, and it is banned in sport.

TyrAlaAspAlaIlePheThrGlnSerTyrArgLysValLeuAlaGlnLeuSerAlaArgLysLeuLeuGlnAspIleLeuSerArgLys
30 amino acids, in order. A double ring marks a mirror-image, modified or non-standard one. End caps, bridges and anything attached to the chain are not drawn. Source: FDA substance registry.
Human evidence
Grade C

Small studies

Completed randomized trials
1
Approved?
No

Not approved in the US or the EU

Sport (WADA)
Banned

On WADA's Prohibited List.

Checked on .

How we count a trial
Short answer

As of September 2026, the FDA and the EMA have not approved CJC-1295. The human evidence is one small study in healthy adults, published in 2006. No long-term safety trial in humans has been published. WADA bans it in sport at all times. It reaches people as an unregulated research chemical, and you cannot tell by looking what a given vial contains.

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What is CJC-1295?

CJC-1295 is a lab-made version of GHRH, the hormone that triggers growth hormone release, changed so that it breaks down more slowly. ConjuChem developed it in the mid-2000s as a candidate to raise growth hormone levels. It never reached approval by the FDA or the EMA, and it circulates as an unregulated research chemical.

Does CJC-1295 work?

In one small study, CJC-1295 raised growth hormone levels in healthy adults over multiple days. Nobody knows whether that brings any benefit, because no trial of health outcomes in humans has been published.

What we found. 1 completed randomized trial counted on the record. The 1 human study listed is a small controlled study in healthy adults, published in 2006. 1 mouse study.

Studies on the CJC-1295 record: each study, what it was tested in, its status and what it shows.
Teichman and colleagues, 2006. A study of what the compound does in the bodyPeoplePublished. A small controlled trialGrowth hormone and IGF-1 stayed raised over multiple days in healthy adults
Study in GHRH knockout mice, which lack GHRHAnimalsPublishedCJC-1295 brought growth back to normal in these mice

The mouse study cannot tell you what happens in people.

How we count a trial

Is CJC-1295 safe?

Nobody knows. The human safety data come from one small published study. No long-term safety trial in humans has been published. In animals, the record holds one mouse study of growth and no safety study. Those gaps belong to the compound. The vial has gaps of its own, set out below.

What is in a vial sold as CJC-1295?

The record says CJC-1295 circulates as an unregulated research chemical and is commonly used for muscle gain, fat loss or anti-aging. It lists no test of a vial sold that way. A "research use only" label guarantees nothing about purity. A certificate of analysis counts only if it names your lot number, a lab with no stake in the result, and the method used. Purity and identity are separate tests.

Three questions to ask the seller:

  1. Which lot number is this certificate for?
  2. Who ran the test, and are they independent of you?
  3. Does the report confirm identity by mass spectrometry, or purity alone?
Score a seller on 20 criteria

What don't we know?

  • Whether it is safe over the long term. No long-term safety trial in humans has been published.
  • Whether raised growth hormone levels bring any benefit. No trial of health outcomes in humans has been published.
  • What it does in anyone other than healthy adults. The one human study enrolled healthy adults.
  • What is in any given vial.

The other side

A personal result is real to the person who had it. It cannot show whether the compound caused it, or what the vial held.

What would change this record?

  • A registered, peer-reviewed Phase 1/2 safety trial in a defined group of people. The record calls it the first real step toward closing the gap.

Change log

  • Record checked. No change logged yet.
Every change on the Table

Three questions to ask next

Ask better questions.

More questions about CJC-1295

Is CJC-1295 approved by the FDA?

No. The FDA has not approved it, and it has no EMA marketing authorisation. The record says it never advanced past one small human study.

Has CJC-1295 been tested in people?

Yes, in one small study. It was published in 2006 and measured growth hormone levels in healthy adults over multiple days.

Is CJC-1295 banned in sport?

Yes, at all times. The record says WADA's Prohibited List names it under GHRH and its analogues.

Is CJC-1295 the same as Modified GRF 1-29?

The record treats them as one. It lists Modified GRF 1-29 and DAC:GRF as other names for CJC-1295. It also describes one variant that binds albumin in the blood, so its effect lasts much longer than natural GHRH. It does not say which name fits which variant.

Are any human trials of CJC-1295 running now?

This record lists none. It holds one published human study and one mouse study.
Sources

Record checked on . Each source shows the date it was checked.

Growth hormone axis

In the same group

All 8 in this group
Still curious

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